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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK3 All Species: 28.48
Human Site: S97 Identified Species: 39.17
UniProt: Q00526 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00526 NP_001249.1 305 35046 S97 Y M D S T P G S E L P L H L I
Chimpanzee Pan troglodytes XP_523720 325 36841 S117 Y M D S T P G S E L P L H L I
Rhesus Macaque Macaca mulatta XP_001102596 305 34903 S97 Y M D S T P D S E L P L H L I
Dog Lupus familis XP_540442 303 34173 S95 Y M D S A P A S E L P L H L V
Cat Felis silvestris
Mouse Mus musculus Q80YP0 303 33870 S97 H M D S S P T S E L P L P V V
Rat Rattus norvegicus Q63699 298 33869 T97 F M D A S A L T G L P L P L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P13863 303 34670 Q98 L D T I P S G Q Y L D R S R V
Frog Xenopus laevis P23437 297 33852 S97 F M D G S N I S G I S L A L V
Zebra Danio Brachydanio rerio NP_998571 298 34001 S97 F M D S T S V S G I S L P L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23572 297 34420 D97 Y M D S L P V D K H M E S E L
Honey Bee Apis mellifera XP_393450 299 34033 G96 K L L D S V K G G L D Q A L V
Nematode Worm Caenorhab. elegans P34556 332 38277 E116 M D Q L G K D E Y L P L E T L
Sea Urchin Strong. purpuratus XP_790847 299 34142 S97 Y M D V A P P S G L P P G L V
Poplar Tree Populus trichocarpa XP_002306004 294 33768 F97 H M D S S P E F A N D P R L V
Maize Zea mays P23111 294 33816 F97 F M D S C P E F A K N P T L I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 F97 H M D S T P D F S K D L H M I
Baker's Yeast Sacchar. cerevisiae P00546 298 34043 Q106 M E G I P K D Q P L G A D I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 96.7 88.5 N.A. 82.6 74.7 N.A. N.A. 63.6 73.7 73.7 N.A. 62.9 67.2 58.1 69.5
Protein Similarity: 100 93.5 98.3 92.7 N.A. 91.8 84.5 N.A. N.A. 78 84.5 83.2 N.A. 76.7 80.6 69.5 82.6
P-Site Identity: 100 100 93.3 80 N.A. 60 46.6 N.A. N.A. 13.3 33.3 46.6 N.A. 33.3 13.3 20 53.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 73.3 N.A. N.A. 20 60 66.6 N.A. 46.6 33.3 26.6 60
Percent
Protein Identity: 65.2 64.2 N.A. 65.5 62.3 N.A.
Protein Similarity: 81.6 80.9 N.A. 81.3 77.7 N.A.
P-Site Identity: 33.3 40 N.A. 53.3 6.6 N.A.
P-Site Similarity: 53.3 46.6 N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 6 12 6 6 0 12 0 0 6 12 0 0 % A
% Cys: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 77 6 0 0 24 6 0 0 24 0 6 0 0 % D
% Glu: 0 6 0 0 0 0 12 6 30 0 0 6 6 6 0 % E
% Phe: 24 0 0 0 0 0 0 18 0 0 0 0 0 0 0 % F
% Gly: 0 0 6 6 6 0 18 6 30 0 6 0 6 0 0 % G
% His: 18 0 0 0 0 0 0 0 0 6 0 0 30 0 0 % H
% Ile: 0 0 0 12 0 0 6 0 0 12 0 0 0 6 36 % I
% Lys: 6 0 0 0 0 12 6 0 6 12 0 0 0 0 0 % K
% Leu: 6 6 6 6 6 0 6 0 0 65 0 59 0 65 12 % L
% Met: 12 77 0 0 0 0 0 0 0 0 6 0 0 6 0 % M
% Asn: 0 0 0 0 0 6 0 0 0 6 6 0 0 0 0 % N
% Pro: 0 0 0 0 12 59 6 0 6 0 48 18 18 0 0 % P
% Gln: 0 0 6 0 0 0 0 12 0 0 0 6 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 6 6 6 0 % R
% Ser: 0 0 0 59 30 12 0 48 6 0 12 0 12 0 0 % S
% Thr: 0 0 6 0 30 0 6 6 0 0 0 0 6 6 0 % T
% Val: 0 0 0 6 0 6 12 0 0 0 0 0 0 6 53 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 36 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _